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FRONTLINE Plus for Dogs Flea and Tick Treatment (Large Dog, 45-88 lbs.) 8 Doses (Purple Box) ( Packaging May Vary )

4.6 4.6 out of 5 stars 4,589 ratings
Amazon's Choice highlights highly rated, well-priced products available to ship immediately.
Amazon's Choice in Dog Flea Drops by Frontline

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About this item

  • Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
  • Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
  • Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days.
  • FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products.
  • Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations.
  • Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus.

Additional Details

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Customer ratings by feature

Easy to use
4.4 4.4
Scent
4.0 4.0
Value for money
3.6 3.6
Flavor
3.2 3.2

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$79.99 ($10.00/Count)
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This Item
FRONTLINE Plus for Dogs Flea and Tick Treatment (Large Dog, 45-88 lbs.) 8 Doses (Purple Box) ( Packaging May Vary )
FRONTLINE Plus for Dogs Flea and Tick Treatment (Large Dog, 45-88 lbs.) 8 Doses (Purple Box) ( Packaging May Vary )
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Price-24% $79.99
List:$104.99
-13% $54.99
List:$62.99
$94.99-13% $54.99
List:$62.99
-10% $17.99
List:$19.99
-12% $79.98
List:$91.18
Delivery
Get it as soon as Sunday, Mar 31
Get it as soon as Sunday, Mar 31
Get it as soon as Sunday, Mar 31
Get it as soon as Sunday, Mar 31
Get it as soon as Sunday, Mar 31
Get it as soon as Sunday, Mar 31
Customer Ratings
Easy to use
4.4
4.4
4.4
4.7
3.2
4.2
Value for money
3.6
3.8
3.8
3.8
1.7
3.5
Flavor
3.2
2.6
2.6
2.1
2.8
Scent
4.0
4.4
4.4
3.0
Comfort
4.6
4.6
2.5
3.5
Sold By
Amazon.com
Amazon.com
Amazon.com
Amazon.com
PETIQ
Amazon.com
target audience
Dogs
Adult
Adult
Adult
Dog, Dog, Dog, Dog, Dog
Dog
age range
All Life Stages
All Life Stages
All Life Stages
All Life Stages
All Life Stages
7 weeks and older
scent
Unscented
No Scent
No Scent
No Scent
Unscented
form
Topical
Stick
Stick
Stick
Drops
Topical
volume
12 milliliters
8.04 milliliters
16.08 milliliters
12.06 milliliters
24 milliliters
active ingredients
fipronil and (S)-methoprene
Fipronil, (S)-methoprene, Pyriproxyfen
Fipronil, (S)-methoprene, Pyriproxyfen
Fipronil, (S)-methoprene, Pyriproxyfen
Fipronil, Cyphenothrin, (S)-methoprene
Imidacloprid, Permethrin, Pyriproxyfen

From the brand


From the manufacturer

Smiling man playing fetch outside with healthy dog. Frontline Plus awarded Newsweek most trusted
Frontline Plus has been trusted by pet owners for over 20 years and kills fleas and chewing lice
Answers to frequently asked questions about Frontline flea and tick prevention and treatment plans

How to Apply FRONTLINE Plus for Dogs

Step one woman reading instructions on pack before applying flea and tick non prescription treatment

Step two woman holding applicator upright and away from her face before opening by snapping off tip

Step three prep dog for flea treatment application by using fingers to part fur so skin is visible

Step four place the open applicator to dogs skin and squeeze out all contents on dog

Read full instructions on packaging before use. Shown here: Size Large 45-88 lbs.

Use scissors to separate one blister. Hold applicator upright with foil side toward you and snap applicator tip off.

Part dog’s hair between shoulder blades until skin is visible.

Place applicator tip directly against exposed skin and apply entire contents directly to the skin. Do not apply on top of hair.

Pack of Frontline Plus for small dog breeds tratamiento de pulgas y garrapatas para perros pequenos Pack of Frontline Plus for medium dog breeds medicina para matar pulgas y garrapatas Pack of Frontline Plus for large dog breeds prevención de pulgas y garrapatas para perros grandes Pack of Frontline Plus for xl dog breeds control de pulgas y garrapatas para perros extra grandes Frontline Plus Cat
FRONTLINE Plus for Small Dogs FRONTLINE Plus for Medium Dogs FRONTLINE Plus for Large Dogs FRONTLINE Plus for X-Large Dogs FRONTLINE Plus for Cats
Customer Reviews
4.4 out of 5 stars
43,549
4.4 out of 5 stars
20,957
4.5 out of 5 stars
13,629
4.6 out of 5 stars
3,617
4.4 out of 5 stars
43,333
Recommended pet size 5 to 22 pounds 23 to 44 pounds 45 to 88 pounds 89 to 132 pounds Cats and kittens over 1.5 pounds
Kills adult fleas, flea eggs, and flea larvae
Kills ticks and chewing lice
Minimum age of pet for use Dogs and puppies 8 weeks and older Dogs and puppies 8 weeks and older Dogs and puppies 8 weeks and older Dogs and puppies 8 weeks and older Cats and kittens 8 weeks and older
Available sizes 3, 6 and 8-Dose 3, 6 and 8-Dose 3, 6 and 8-Dose 3, 6 and 8-Dose 3, 6 and 8-Dose
Do not use on cats Do not use on cats Do not use on cats Do not use on cats For use on cats only

Product Description

Keep your dog protected with the #1 name in flea & tick protection*, FRONTLINE®. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years**— FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: *Data on file at Boehringer Ingelheim. **Data showing 20 years of trust in killing fleas and ticks is on file at Boehringer Ingelheim.

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Warranty & Support

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FRONTLINE

FRONTLINE Plus for Dogs Flea and Tick Treatment (Large Dog, 45-88 lbs.) 8 Doses (Purple Box) ( Packaging May Vary )


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Important information

Safety Information

KEEP OUT OF REACH OF CHILDREN. WARNING: PRECAUTIONARY STATEMENTS - HAZARDS TO HUMANS: WARNING. Causes substantial but temporary eye injury. Do not get in eyes or on clothing. Avoid Contact with skin. Harmful if swallowed. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash clothing that may have come in contact with the product before reuse. HAZARDS TO DOMESTIC ANIMALS: For external use on dogs ONLY. Do not use on animals other than dogs. Do not use on dogs under 9 weeks of age or weighing less than 5 lbs. Individual sensitivities may occur after using ANY pesticide product. Dogs may experience some temporary irritation at the site of product application. If signs of sensitivity occur, bathe your dog with mild soap or shampoo and rinse with large amounts of water. If signs of sensitivity occur and persist, contact a veterinarian immediately. If your dog has an unusual reaction to the initial application, consult a veterinarian before repeating application. Certain medications can interact with pesticides. Consult a veterinarian before using on medicated, debilitated, aged, pregnant or nursing dogs, or dogs known to be sensitive to pesticide products. Consult a veterinarian for guidance on use against Sarcoptes mites. This product is not a substitute for a prescribed heartworm preventative.nCall 1-888-637-4251, for assistance. PHYSICAL OR CHEMICAL HAZARDS: Do not allow this product to come in contact with an oxidizing agent, as a hazardous chemical reaction may occur Harmful if swallowed. Causes substantial but temporary eye injury. Do not get in eyes or on clothing. Avoid contact with skin. Wear (specify appropriate protective eyewear such as goggles, face shield, or safety glasses). Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse.

Directions

1. Part your dog's hair at the shoulder blades. 2. Apply content of applicator to the skin. 3. Repeat every 30 days for continuous protection.

Customer reviews

4.6 out of 5 stars
4.6 out of 5
4,589 global ratings

Customers say

Customers like the ease of use and quality of the pet pest control product. For example, they mention the instructions are clear, and it works well. Opinions are mixed on performance and value.

AI-generated from the text of customer reviews

14 customers mention14 positive0 negative

Customers find the pet pest control easy to use. They say the instructions are clear, it works great fast, and is convenient and easy to keep track of. Customers also say it's a great product and easy get.

"...Super easy and effective." Read more

"I’ve been using Frontline for years on my dogs. It’s easy to use and they never had any ticks or fleas." Read more

"...Works great fast and complete easy to use lots of good packaging to stay safer." Read more

"...This product is easy to use and seemed to work well at preventing fleas and ticks...." Read more

8 customers mention8 positive0 negative

Customers are satisfied with the quality of the pet pest control. They mention it works well, is dependable, and lasts as long as it says. Some say it's perfect for their dog and can be used on pregnant and nursing dogs.

"I like frontline because it can also be used on pregnant and nursing dogs and as a German shepherd breeder this is important...." Read more

"...still carries the oral medication, it's far more effective, lasts as long as it says, and it's in the form of a small treat the enjoys...." Read more

"perfect for our dog. great product and easy to get." Read more

"Dependability. Works well on our pets" Read more

95 customers mention58 positive37 negative

Customers are mixed about the performance of the pet pest control. Some mention that it works well at preventing fleas and ticks, while others say that it doesn't work at all and loses effectiveness after 2 or 3 swims in the lake.

"...My dogs appear to tolerate this flea medication well. Have been administering for over 3 plus years." Read more

"...We thought we could switch to Frontline but it just doesn't work. We've had to use tweezers to remove ticks attached to all parts of his body...." Read more

"...It should never be eaten. Seems to keep fleas and ticks off well, though. I will continue to use it." Read more

"Since we started using this, we have had no issue with fleas. Just give our pup a bath one night, and the next morning we put this on her...." Read more

39 customers mention23 positive16 negative

Customers are mixed about the value of the pet pest control product. Some mention that it works well, is a little costly, and is good value, while others say that it's a waste of money and not worth it for a pup.

"good value fast ship" Read more

"...We're back on Brevecto from the vet. Not worth it for a pup who lives in the woods and loves to explore nature." Read more

"...This is a great price for the size package." Read more

"...Very disappointed especially for the price." Read more

5 customers mention3 positive2 negative

Customers are mixed about the protection of the pet pest control product. Some mention that it provides excellent protection, while others say that it doesn't work at protecting their dog from fleas and ticks.

"...Works great fast and complete easy to use lots of good packaging to stay safer." Read more

"...Bought this mostly from name recognition. It just simply does not work at protecting our dog from fleas and ticks...." Read more

"Protects my livestock guardian dogs in the most harsh southern conditions. Do not expect it to work beyond one month...." Read more

"These drops did NOT repel, or kill the fleas on our dogs. If anything the fleas thrived on it!Maybe it's because these are GEORGIA FLEAS!" Read more

Works great!
5 Stars
Works great!
My dog hasn't had a flea or tic on him since I started about 3 years ago. We live in the woods, walking where every possible animial walks (even bears). My dog is so clean of bugs that indoor cat has been safe without any flea or tic treatment.
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5.0 out of 5 stars Works great!
Reviewed in the United States on March 17, 2024
My dog hasn't had a flea or tic on him since I started about 3 years ago. We live in the woods, walking where every possible animial walks (even bears). My dog is so clean of bugs that indoor cat has been safe without any flea or tic treatment.
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