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FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)

4.4 4.4 out of 5 stars 43,549 ratings
Amazon's Choice highlights highly rated, well-priced products available to ship immediately.
Amazon's Choice in Dog Flea Drops by Frontline

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About this item

  • Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
  • Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control.
  • Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days.
  • FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products.
  • Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations.
  • Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus.

Customer ratings by feature

Easy to remove
4.0 4.0
Easy to use
3.9 3.9
Scent
3.5 3.5
Comfort
3.4 3.4

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This Item
FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)
FRONTLINE® Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 3 Doses (Orange Box)
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NEXTSTAR Flea and Tick Prevention for Dogs, Repellent, and Control, Fast Acting Waterproof Topical Drops for Small Dogs, 1 Month Dose
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Price-18% $40.98
List:$49.99
$94.99$82.98-13% $54.99
List:$62.99
$94.99-10% $17.99
List:$19.99
Delivery
Get it as soon as Sunday, Mar 31
Get it as soon as Sunday, Mar 31
Get it as soon as Sunday, Mar 31
Get it as soon as Sunday, Mar 31
Get it Apr 2 - 4
Get it as soon as Sunday, Mar 31
Customer Ratings
Easy to use
3.9
4.0
4.2
4.4
3.9
3.3
Value for money
2.9
3.0
2.9
3.8
2.5
1.7
Scent
3.5
3.6
3.5
4.4
3.5
Flavor
2.7
1.9
4.6
2.6
2.1
Comfort
3.4
4.6
2.4
Sold By
Amazon.com
Amazon.com
Amazon.com
Amazon.com
Petco
PETIQ
target audience
Dog, Dog, Dog Flea And Tick, Dog Flea And Tick Topicals, PetSupplies
Adult
Dog
Adult
Adult
Dog, Dog, Dog, Dog, Dog
age range
All Life Stages
All Life Stages
All Life Stages
All Life Stages
All Life Stages
All Life Stages
scent
Orange
No Scent
Topical
No Scent
No Scent
form
Stick
Stick
Stick
Stick
Drops
volume
264.5 milliliters
4.02 milliliters
3 milliliters
8.04 milliliters
8.04 milliliters
active ingredients
Fipronil 9.8% & (S)-methoprene 8.8%.
Fipronil, (S)-methoprene, Pyriproxyfen
Fipronil, Permethrin, Pyriproxyfen
Fipronil, (S)-methoprene, Pyriproxyfen
Fipronil, (S)-methoprene, Pyriproxyfen
Fipronil, Cyphenothrin, (S)-methoprene

From the brand


From the manufacturer

Smiling man playing fetch outside with healthy dog. Frontline Plus awarded Newsweek most trusted
Frontline Plus has been trusted by pet owners for over 20 years and kills fleas and chewing lice
Answers to frequently asked questions about Frontline flea and tick prevention and treatment plans

How to Apply FRONTLINE Plus for Dogs

Step one woman reading instructions on pack before applying flea and tick non prescription treatment

Step two woman holding applicator upright and away from her face before opening by snapping off tip

Step three prep dog for flea treatment application by using fingers to part fur so skin is visible

Step four place the open applicator to dogs skin and squeeze out all contents on dog

Read full instructions on packaging before use. Shown here: Size Large 45-88 lbs.

Use scissors to separate one blister. Hold applicator upright with foil side toward you and snap applicator tip off.

Part dog’s hair between shoulder blades until skin is visible.

Place applicator tip directly against exposed skin and apply entire contents directly to the skin. Do not apply on top of hair.

Pack of Frontline Plus for small dog breeds tratamiento de pulgas y garrapatas para perros pequenos Pack of Frontline Plus for medium dog breeds medicina para matar pulgas y garrapatas Pack of Frontline Plus for large dog breeds prevención de pulgas y garrapatas para perros grandes Pack of Frontline Plus for xl dog breeds control de pulgas y garrapatas para perros extra grandes Frontline Plus Cat
FRONTLINE Plus for Small Dogs FRONTLINE Plus for Medium Dogs FRONTLINE Plus for Large Dogs FRONTLINE Plus for X-Large Dogs FRONTLINE Plus for Cats
Customer Reviews
4.4 out of 5 stars
43,549
4.4 out of 5 stars
20,957
4.5 out of 5 stars
13,629
4.6 out of 5 stars
3,617
4.4 out of 5 stars
43,333
Recommended pet size 5 to 22 pounds 23 to 44 pounds 45 to 88 pounds 89 to 132 pounds Cats and kittens over 1.5 pounds
Kills adult fleas, flea eggs, and flea larvae
Kills ticks and chewing lice
Minimum age of pet for use Dogs and puppies 8 weeks and older Dogs and puppies 8 weeks and older Dogs and puppies 8 weeks and older Dogs and puppies 8 weeks and older Cats and kittens 8 weeks and older
Available sizes 3, 6 and 8-Dose 3, 6 and 8-Dose 3, 6 and 8-Dose 3, 6 and 8-Dose 3, 6 and 8-Dose
Do not use on cats Do not use on cats Do not use on cats Do not use on cats For use on cats only

Product guides and documents

Looking for specific info?

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Product Dimensions ‏ : ‎ 5.75 x 0.75 x 4.5 inches; 0.16 ounces
  • Item model number ‏ : ‎ 74273
  • Department ‏ : ‎ Flea & Tick
  • Date First Available ‏ : ‎ October 2, 2001
  • Manufacturer ‏ : ‎ Boehringer Ingelheim Animal Health
  • ASIN ‏ : ‎ B00008DFGY
  • Country of Origin ‏ : ‎ France
  • Customer Reviews:
    4.4 4.4 out of 5 stars 43,549 ratings

Product Description

Keep your dog protected with the #1 name in flea & tick protection*, FRONTLINE®. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years**— FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: *Data on file at Boehringer Ingelheim. **Data showing 20 years of trust in killing fleas and ticks is on file at Boehringer Ingelheim.

Important information

Safety Information

KEEP OUT OF REACH OF CHILDREN. WARNING: PRECAUTIONARY STATEMENTS - HAZARDS TO HUMANS: WARNING. Causes substantial but temporary eye injury. Do not get in eyes or on clothing. Avoid Contact with skin. Harmful if swallowed. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash clothing that may have come in contact with the product before reuse. HAZARDS TO DOMESTIC ANIMALS: For external use on dogs ONLY. Do not use on animals other than dogs. Do not use on dogs under 9 weeks of age or weighing less than 5 lbs. Individual sensitivities may occur after using ANY pesticide product. Dogs may experience some temporary irritation at the site of product application. If signs of sensitivity occur, bathe your dog with mild soap or shampoo and rinse with large amounts of water. If signs of sensitivity occur and persist, contact a veterinarian immediately. If your dog has an unusual reaction to the initial application, consult a veterinarian before repeating application. Certain medications can interact with pesticides. Consult a veterinarian before using on medicated, debilitated, aged, pregnant or nursing dogs, or dogs known to be sensitive to pesticide products. Consult a veterinarian for guidance on use against Sarcoptes mites. This product is not a substitute for a prescribed heartworm preventative.nCall 1-888-637-4251, for assistance. PHYSICAL OR CHEMICAL HAZARDS: Do not allow this product to come in contact with an oxidizing agent, as a hazardous chemical reaction may occur Harmful if swallowed. Causes substantial but temporary eye injury. Do not get in eyes or on clothing. Avoid contact with skin. Wear (specify appropriate protective eyewear such as goggles, face shield, or safety glasses). Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Remove and wash contaminated clothing before reuse.

Ingredients

Fipronil (9.8%)|(S)-Methoprene (8.8%)

Directions

Directions for Use Step 1. To REMOVE Applicator: 1. Use scissors to separate one blister; 2. Use scissors to cut along dotted line; 3. Peel down foil to remove the applicator. Step 2. OPEN Applicator. Hold upright with foil side toward you and snap applicator tip. Step 3. APPLY FRONTLINE Plus. Part the dog’s hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the dog’s skin. Do not apply on top of the hair coat. Avoid contact with treated area until dry. Do not allow your dog to ingest the product. Do not apply to dogs weighing less than 5 lbs. or younger than 8 weeks of age. Do not use more than one application per dog per month. Frequency Use monthly to control fleas and ticks. Do not reapply FRONTLINE Plus for 30 days.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.

Customer reviews

4.4 out of 5 stars
4.4 out of 5
43,549 global ratings

Customers say

Customers like the protection provided by the pet supplies. They say it consistently protects their animals from fleas and ticks. They are also happy with the ease of use. However, some customers have reported issues with the durability of the product. Opinions are mixed on comfort, value, and quality.

AI-generated from the text of customer reviews

228 customers mention218 positive10 negative

Customers find the pet supplies pretty straight forward to use. They say it's easy to apply monthly, and the impact of applying the product is almost immediate. Customers also say it comes in a convenient 3 pack, and is a money-saver.

"Easy product to work with. Our vet prefers this over injections, which sometimes have complications...." Read more

"...Wish it wasn't so expensive but it is easy to use." Read more

"Rub it on the neck and it works no pills to swallow.Easy to use" Read more

"...It is a highly effective and easy-to-use treatment that has helped keep my dog free from fleas and ticks...." Read more

120 customers mention90 positive30 negative

Customers like the ticks. They mention that the product repels ticks very well, and has helped with ticks in the past. Some say that it kills tick better.

"Have been using this product for years. It kills ticks on my dog and probably helps keep others off...." Read more

"...Since using it, we have not seen 1 tick or flea on our dogs. That's saying something!!..." Read more

"...No ticks or fleas in 3 years ,and we walk every day." Read more

"...in the past but using it this year I feel like it is attracting the ticks not deterring them. Not sure if I got a bad box but IT Is NOT working...." Read more

96 customers mention80 positive16 negative

Customers like the protection of the pet supplies. For example, they say it works to protect their animals for many years, consistently protects them from ticks, and is safe for them to eat. Some mention that it provides fair protection, while others say it provides undisputed gold standard of protection against parasites.

"...with fipronil and (S)-methoprene, which are both safe and effective ingredients that have been approved by the EPA for use on dogs...." Read more

"Protects dog from fleas & ticks. Saves money so I don’t have to buy at vet or retail store." Read more

"...This product protects my dog from fleas, ticks etc." Read more

"The product is easy to use for lasting protection." Read more

3,206 customers mention1,617 positive1,589 negative

Customers are mixed about the quality of the pet supplies. Some mention that it works well against fleas and ticks, and is the best flea and tick medication that you can get over the counter. However, others say that it didn't work and the flea problem was just as bad as before using the treatment.

"...This one has worked very well with NO irritation, NO seizures and has kept the fleas off, which this year we struggled with because it never got..." Read more

"...Cape Cod proved to me beyond doubt that Frontline Plus also no longer worked on ticks...." Read more

"...It kills ticks on my dog and probably helps keep others off. My dog has never gotten fleas while using this product." Read more

"...It just did not work at all. The fleas have become immune to it. Or I just got a bad batch. It cost a lot to me being retired. I will not buy it again" Read more

957 customers mention628 positive329 negative

Customers are mixed about the value of the pet supplies. Some mention that it's a good price and worth the cash, while others say that it’s s eepy and not cheap.

"...receiving it it came fast it came well shipped and packaged the price was great just the quality of the product seems to have degraded and I think I..." Read more

"Works as ordered. A little expensive but works" Read more

"...Frontline Plus is WORTH the cash..." Read more

"Good price" Read more

211 customers mention86 positive125 negative

Customers are mixed about the comfort of the pet supplies. Some mention that it works and makes their dog stop itching within a few days. They say the treatment does not irritate their skin at all. However, other customers say that their dogs still show signs of itching and biting.

"...the Frontline and 3 weeks later he is still scratching and biting at his skin like crazy and I am still seeing fleas...." Read more

"...No more new bites on my dogs bellies and no more insane scratching. It works, just gradually (which is realistic anyhow)...." Read more

"...It's such a weird runny feeling and I try to quickly rub it in.So, I do recommend this!..." Read more

"...Seems to dry quickly. She doesn’t have any itchy episodes. And she’s a small dog, but have failed to find any fleas or ticks on her...." Read more

63 customers mention33 positive30 negative

Customers are mixed about the side effects of the pet supplies. Some mention that they have never had any side effects, while others say that it's very toxic and like poison.

"...treatment did not irritate my dog's skin at all, and he hasn't had any adverse reactions after licking himself...." Read more

"...Though they said it was harmless, the smell of the pill was awful. Like poison. And a pill pocket didn't help. Just prefer the topical treatment...." Read more

"...Never a bad reaction or side effect either, you just cannot go wrong with this product!..." Read more

"...This product is highly dangerous and I do not recommend it to anyone, not even my worst enemy!! I have a pure bred shih tzu..." Read more

65 customers mention18 positive47 negative

Customers are dissatisfied with the durability of the pet supplies. They mention that it did not last, it wore off in less than 2 weeks, and it is weak. Some say that the product wears off quicker with water.

"...in-store decided to order online did not seem to last as long wore off really quickly." Read more

"...Doesnt last 30 days and youre lucky if you get 15 days befor you need another dose. Will not buy again." Read more

"...in my experience, one dose lasts several months. I was pleased to find the product on Amazon...." Read more

"...Seems to work, but absolutely wears off around 4.5-5 weeks. You have to be diligent in reapplication during warm months...." Read more

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